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(brand name is Celexa) had reached about $100 per week, while the average costs for generic oxycodone (brand name is Percocet) had hit a record of over $500 per week. However, in December, the prices plummeted, price of topamax plummeted by half, and more than half of the patients taking both drugs received their prescriptions for only one pill at a time, according to an analysis of government regulatory records.
Experts say that's because companies making opioid drugs have increased their lobbying of legislators to pressure them support tighter rules and new regulations. "Some of these companies, especially, have been lobbying very strongly in the last few years," says Dr. David Allison, an emergency room physician who directs cost of generic topamax
the Johns Hopkins Center for Injury Control and Prevention is an advocate for drug patients in Baltimore. "They use every means they have to try ensure that it's as difficult possible to get an opioid."
The result of all lobbying, says Allison, has been that most federal regulation is "not good public health policy." Some drugs, like oxycodone, which is manufactured by Purdue Pharma, have been marketed as safe to most people, but some do not make it to the market because they're misbranded, or the FDA has been too slow in issuing approvals for them. Oxycodone is one such case where the FDA wasn't doing its job. In an interview with The Washington Post, former head of the FDA's drug-approval division said some drugs were delayed "because of political pressures from the pharmaceutical industry that were related to marketing strategies."
Because of those political pressures, drugs have been delayed for a long time. The FDA still needs to issue six new opioid approvals a year, but not enough to make a huge dent in the epidemic. And drug companies have been lobbying legislators for some time now. Before the election, they spent more than $700,000 on lobbying. They're also suing some politicians to try block state regulations.
The pharmaceutical industry has been spending more than $1.6 billion every year to lobby federal lawmakers and agencies since 2009 â€” up from $700,000 in 2008 and $150,000 2007 â€” according to research by the Public Citizen group in United States. And it's not only lobbying over patient privacy protection â€” it's also doing it around the time Congress and White House are trying to find ways treat pain using new drug-approval processes.
In March, Purdue Pharma and five partners came to Congress tell lawmakers about its new formulation of oxycodone, and tried to convince them that a special review process to approve medications under the Food and Drug Administration's priority review process was unnecessary, says Sen. Sherrod Brown. Purdue Pharma has asked the FDA to reconsider its approval of OxyContin to treat severe pain. It's already been approved for use short-term use.
"I would suggest that we might give them a pass on this," Brown says. "This seems to me be highly problematic."
To fight back, Brown is proposing several new regulations, which would require the FDA to consider all information that doctors, consumers and the public need when deciding whether to approve a drug. This information includes prescribing patterns, drug price trends and evidence about how the new drug is affecting consumer markets of pharmacies and doctors. If the FDA were to start from scratch, Brown says, it would have a shorter time frame to approve a new opioid treat pain. But it would also have the time to do proper scientific research about canada drug pharmacy new drugs, he says.
The FDA says it's working on these requests but hasn't released a detailed timetable. The agency says it needs more information before can make any decisions about new opioid approval.
A senior industry lawyer, who requested anonymity because he didn't want to jeopardize his job, says that companies shouldn't worry too much about new regulations. "It's difficult for companies to put together evidence show how each individual drug fits in with the others," lawyer says. "They've had lots of time. They haven't shown any significant pattern of failures."
The industry might not need new regulations, though, if Congress passes a law that makes it tougher to get drugs market. Some proposals are already out there, and one that passed in 2014 to crack down on misbranding Topamax 100mg $261.56 - $2.18 Per pill is in the president's budget.
It's unclear if the administration will push to pass something now, after seeing the slow movement on new policies to treat pain. The U.S. Environmental Protection Agency announced Thursday it had identified 2,320 incidents of potential human exposure to chemicals that can cause cancer, birth defects or other health problems, including 2,032 involving employees of Pioglitazone cost
facilities run by DuPont and PPG Industries, which has been a longtime DuPont supplier. The American people have not yet witnessed, in any way, a "war on women"
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Medical Disclaimer WASHINGTON â€” The Environmental Protection Agency said on Wednesday it was investigating the spill of a toxic substance into the Animas River in northwestern Colorado from a company that had operated an abandoned mine for decades.
The spill of wastewater, containing arsenic, was likely from a malfunctioning storm-water drainage system, the Colorado River Basin Commission, which is the federal agency with jurisdiction over the river, said on Wednesday.
The Associated Press reported that spill was detected on Wednesday evening near the town of Silverton, which shares a boundary with the Animas river and where residents have been warned to stay indoors from 6 p.m. on Wednesday to avoid being exposed.
Agents from the EPA's chemical and waste unit were deployed by helicopter and river boat to the in early afternoon Wednesday. At White House, Obama asked for a briefing from Mattis on how the military and state local officials were handling the security situation in Libya.
Obama said that he had received the briefings on Libyan strategy and military operations that he hoped the Pentagon would make available "resources and expertise" in Libya.
The president also asked for Mattis's advice on the strategy to handle humanitarian crisis in Syria. The United States does not back Syrian rebel opposition groups, even though it has designated them a terrorist group. The United States and Russia have also been in direct discussions about an international cease-fire there. As the federal Liberals push back against the Conservative opposition over cost of their proposed national tax on pot, an NDP MP wants the government to prove its claims taxpayers that legalization could save money.
NDP MP Charlie Angus, an from the neighbouring region of Ontario, wants to know what the math is behind government's claim legalization Topamax 100mg $87.55 - $2.92 Per pill will save the taxpayer $1.2 billion a year.
In a letter to Finance Minister Bill Morneau, Angus asks if the federal government will actually end up saving the government $125 million or at least a year after the $1.4-billion worth of annual cannabis revenues is brought into the Canadian economy for tax purposes.
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this claim is completely unsupported and without basis," he wrote.
"The government has provided no evidence or information to substantiate the claim."
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estimates told CBC News he has never seen a government give financial estimate for so long as to include recreational legalization.
"You can't put a price on the freedom of Canadians. This is a fundamental principle of finance," said Michael Veall, a former assistant finance minister for the Ontario Government.
Michael Veall analyzes the math behind Conservative plan to sell pot. (Michael Veall)
But that's just what the Liberals and their officials claim. They've been saying the tax on cannabis will generate $1.4 billion by 2020, and while they're not suggesting they'll pay that amount pharmacy online australia discount code out of general tax revenue, they are saying Ottawa will have plenty to spend â€” the money was never meant to go into general revenue, but instead to deal with the issue of legalization.
In an interview with CBC News, the finance minister himself put cost of legalization at $2.9 billion. Morneau is suggesting that amount will disappear into the government's consolidated revenue streams.
The marijuana industry would raise $10.2 billion in tax 2020, according to an expert
However, an expert in budgeting for the marijuana industry said numbers don't add up.
"Cannabis producers are only licensed to get a 15 per cent rate of tax, so not a whole lot," said Alex Dudley, an economic analyst at the consulting firm IHS Markit. "The revenue they are reporting is probably just a rough number. How much actual revenue is that when you're talking about a $1.4 billion budget the government will end up borrowing to spend deal with?
"All the government's saying they'll be able to get is a share of the revenue. And we're estimating they're going to owe Canadians $125 million get a share of the revenue."
Dudley also noted that the Liberal government plans to have a marijuana market worth $8-billion within 12 months of legalization. The number is based on a report by Mark Jaccard and Steven Hoffman published in the Canadian Medical Association Journal in 2013.
Jaccard and Hoffman said the government should start taxing pot like alcohol, which already brings in about $3.7 billion a year. Instead of taxing it like alcohol, they propose the government collect a 5-per-cent excise tax on.
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